MGF
Also known as: Mechano Growth Factor, IGF-1Ec, IGF-1 Eb (rodent splice variant)
animal onlyWADA bannedNot FDA approvedResearch only
Published Dose Range
No published dosing data available.
Published Cycle Range
No published cycle data available.
Administration
Routessubcutaneous, intramuscular
FrequencyNo data
No published human dosing trials. The endogenous splice variant exists in human muscle, but synthetic MGF protocols are not supported by peer-reviewed dose-finding data.
Safety Profile
Contraindications
- • Active or history of malignancy (theoretical, mechanism-based)
Common side effects
- • Insufficient human data to characterize
Serious risks
- • Theoretical risk of accelerating occult malignancy (IGF-1 axis activation)
- • Long-term safety unknown
Drug interactions
- • Insufficient human data
Pregnancy / breastfeeding
Avoid — no human safety data
Common Misconceptions
- MGF is a splice variant of IGF-1 (IGF-1Ec in humans), not a separate growth factor
- Synthetic MGF marketed for muscle repair has very short half-life and is largely degraded systemically — anabolic claims rest on rodent data
Next Steps
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