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SARM

YK-11

preclinical onlyWADA bannedNot FDA approvedResearch only
Mechanism of Action

YK-11 is a catalog-expanded sarm entry in ProtoComp's source-backed compound corpus. It is included for search, calculator math, stack awareness, and future research curation based on add sarm category and seed, expand compound catalog, explicit_target_list, local_seed, project_target, wiki_sarm, wikipedia_table. Published dosing, cycle length, and clinical-use claims are intentionally left null until compound-specific evidence is reviewed.

Recorded Dose Range
Low5 mg/day
Typical5-10 mg/day
High15 mg/day

Marketed as a SARM but classified as a steroidal myostatin modulator in the literature. No published human trials — dosing is anecdotal.

Recorded Cycle Range
Short4 wks
Typical6 wks
Long8 wks

Short cycles recommended due to hepatotoxicity concerns and lack of human safety data.

Off-cycle: 8 weeks

Administration
Routesoral
FrequencyTwice daily
Preferred timingSplit AM/PM

Short half-life ~6 hours — usually split into 2 doses.

Recorded Cautions

Contraindications

  • Liver disease
  • Cardiovascular disease
  • Pregnancy

Common side effects

  • HPG axis suppression
  • Hair shedding
  • Aggression

Serious risks

  • Hepatotoxicity — steroidal structure, higher liver stress than non-steroidal SARMs
  • Tendon issues reported anecdotally
  • Long-term safety completely unknown — no human trials

Drug interactions

  • Avoid with hepatotoxic compounds

Requires monitoring

  • Liver function
  • Testosterone
  • Creatine kinase

Pregnancy / breastfeeding

Contraindicated

Sex-Specific Notes

Male

Strong suppression expected

Female

Not recommended — no female data and virilization risk

Common Misconceptions
  • Often mislabeled as "non-suppressive myostatin inhibitor" — HPG suppression is documented
  • Steroidal structure — closer to a designer steroid than a non-steroidal SARM
Next Steps

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